Gene LTF
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Also known as
lactotransferrin, lactoferrin, HLF2, GIG12Overview
LTF (Lactotransferrin) encodes lactoferrin, an iron-binding glycoprotein found in breast milk, saliva, tears, and other mucosal secretions. Lactoferrin has multiple functions including antimicrobial activity, iron sequestration, immune modulation, and anti-inflammatory effects. It is particularly important in breast milk where it provides innate immune protection to nursing infants.Variants in LTF can affect lactoferrin production and function, potentially influencing infant immune development and maternal-infant iron transfer during lactation. Lactoferrin levels in breast milk vary significantly among women and may be influenced by genetic factors. The protein also plays roles in adult immunity and has been studied for therapeutic applications.
Understanding your LTF genetic status provides insights into lactoferrin production and innate immunity. This information is particularly relevant for understanding breast milk composition and quality, infant nutrition during breastfeeding, and mucosal immune defense.