Gene KRT75
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Also known as
keratin 75, type II keratin K6hf, K6HF, hair follicle keratinOverview
KRT75 (Keratin 75) encodes a type II intermediate filament keratin protein specifically expressed in hair follicle companion layer cells and the inner root sheath. This keratin provides structural support to the hair follicle and contributes to proper hair shaft formation. KRT75 is part of the keratin family that forms the structural framework of epithelial cells.Variants in KRT75 have been associated with pseudofolliculitis barbae (razor bumps) and may influence hair texture and curl pattern. The A12T polymorphism affects keratin structure and is more common in individuals of African descent. This variant may influence hair follicle morphology and susceptibility to ingrown hairs after shaving.
Understanding your KRT75 genetic status provides insights into hair follicle biology and skin structure. This information is relevant for understanding hair characteristics, susceptibility to folliculitis, and potentially guiding hair care and shaving practices.