Gene GPC5
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Also known as
glypican 5, glypican proteoglycan 5Overview
GPC5 (Glypican 5) encodes a heparan sulfate proteoglycan that is attached to the cell surface via a glycosylphosphatidylinositol anchor. Glypicans regulate various growth factor signaling pathways and play important roles in cell growth, differentiation, and morphogenesis during development.GPC5 has been implicated in several important physiological processes and disease states. Variants near GPC5 have been associated with lung function and chronic obstructive pulmonary disease (COPD) risk in genome-wide association studies. The gene is also expressed in the brain where it influences neuronal development and synapse formation.
Understanding your GPC5 genetic status may provide insights into developmental processes and disease susceptibility. This gene is relevant for understanding the genetic basis of lung function and respiratory health.