Gene CETP

Also known as

HDLCQ10, cholesteryl ester transfer protein

Overview

CETP (Cholesteryl Ester Transfer Protein) encodes a plasma protein that facilitates the transfer of cholesteryl esters and triglycerides between lipoproteins. CETP moves cholesterol from HDL ("good" cholesterol) to LDL and VLDL particles, playing a central role in reverse cholesterol transport and lipid metabolism.

Genetic variants that reduce CETP activity are associated with increased HDL cholesterol levels and have been linked to longevity and reduced cardiovascular disease risk in some populations. The common TaqIB polymorphism (rs708272) affects CETP activity and HDL levels. Individuals with reduced CETP function tend to have larger, more stable HDL particles.

Understanding your CETP genetic status provides insights into your lipid metabolism and cardiovascular risk profile. This information can help guide dietary and lifestyle interventions aimed at optimizing cholesterol levels and cardiovascular health.

NutraHacker Raw DNA Analysis Products that include this gene

• Complete Mutation Nutrition Report

Upload raw DNA data to get your very own analysis of gene CETP through your personalized DNA reports.