Gene MDGA2
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Also known as
MAMDC1, c14_5286Overview
MDGA2 (MAM domain-containing glycosylphosphatidylinositol anchor 2) is a gene that codes for the MDGA2 protein, which is a member of the MAM domain-containing protein family. MAM domain-containing proteins are a group of proteins that are known to play a role in cell-to-cell communication, intracellular signaling, and membrane trafficking.
The MDGA2 protein is a type of cell surface protein, which is typically found on the surface of neurons and is involved in the formation of synapses, which are the points of communication between nerve cells. This protein is also involved in the formation of the signaling complex between the nerve cells and it helps in the regulation of the neural activity and the formation of the neural network.
Studies have suggested that variations in the MDGA2 gene may be associated with an increased risk of certain neurological disorders such as autism, schizophrenia, and intellectual disability. Some studies suggest that the MDGA2 protein may be a target for the development of new therapies for these disorders.
It is also worth mentioning that MDGA2 is a member of a family of proteins that are known to be involved in the formation of the synapse, and other members of this family have been linked to other neurological disorders such as Alzheimer's disease and Parkinson's disease.