Gene GLUT2

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Also known as

SLC2A2

Overview

GLUT2 is a gene that codes for a protein called glucose transporter 2. This protein is a type of glucose transporter, which are proteins that transport glucose (a simple sugar) across the cell membrane. Glucose is an important source of energy for the body, and it is essential for the proper functioning of many tissues and organs.

Glucose transporter 2 is expressed in several tissues, including the liver, pancreas, and small intestine. In the liver and pancreas, it plays a role in the regulation of blood glucose levels. In the small intestine, it helps to absorb glucose from the diet and transport it into the bloodstream.

Mutations in the GLUT2 gene can cause a variety of problems, including abnormalities in glucose metabolism and an increased risk of type 2 diabetes. Some rare genetic disorders, such as Fanconi-Bickel syndrome and maturity-onset diabetes of the young type 5, are caused by mutations in the GLUT2 gene.



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