Gene FADS1

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Also known as

D5D, FADS6, FADSD5, LLCDL1, TU12

Overview

FADS1 is a gene that encodes a protein called fatty acid desaturase 1. This protein is involved in the synthesis of long-chain polyunsaturated fatty acids (LCPUFAs), which are essential for the proper functioning of cells in the body. LCPUFAs are important for the development and function of the brain and are also involved in the regulation of inflammation and immune function.

FADS1 plays a key role in the synthesis of two LCPUFAs called docosahexaenoic acid (DHA) and arachidonic acid (AA). DHA is particularly important for the development and function of the brain, while AA is involved in the regulation of inflammation.

Mutations in the FADS1 gene have been linked to an increased risk of certain health conditions, including cardiovascular disease and type 2 diabetes. Some studies have also suggested that variations in the FADS1 gene may be associated with differences in the metabolism of LCPUFAs, which could affect the risk of certain health conditions.

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