Gene ELOVL5

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Also known as

HELO1, SCA38, dJ483K16.1

Overview

ELOVL5 is a gene that encodes a protein called ELOVL fatty acid elongase 5. This protein is involved in the synthesis of very long-chain polyunsaturated fatty acids (VLCPUFAs), which are a type of long-chain polyunsaturated fatty acid (LCPUFA) that are essential for the proper functioning of cells in the body. VLCPUFAs are important for the development and function of the brain and are also involved in the regulation of inflammation and immune function.

ELOVL5 plays a key role in the synthesis of a VLCPUFA called docosapentaenoic acid (DPA). DPA is involved in the development and function of the brain and is also involved in the regulation of inflammation.

Mutations in the ELOVL5 gene have been linked to an increased risk of certain health conditions, including cardiovascular disease and type 2 diabetes. Some studies have also suggested that variations in the ELOVL5 gene may be associated with differences in the metabolism of VLCPUFAs, which could affect the risk of certain health conditions.

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