Gene CYP2C9

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Also known as

CPC9, CYP2C, CYP2C10, CYPIIC9, P450-2C9, P450IIC9

Overview

The CYP2C9 (Cytochrome P450 2C9) gene was first identified in the late 1970s, when researchers were studying the metabolism of drugs and other chemicals in the liver. The CYP2C9 gene encodes a protein called cytochrome P450 2C9, which is an enzyme that is involved in the metabolism of a wide range of drugs and other chemicals. CYP2C9 is a member of the cytochrome P450 enzyme family, which is named after the pigment that gives the proteins their characteristic color. CYP2C9 is found in the liver and other tissues, and it plays a key role in the metabolism of many drugs, including aspirin, warfarin, and some statins. The activity of CYP2C9 can be affected by genetic variations, and these variations can affect an individual's ability to metabolize certain drugs, leading to differences in drug response and toxicity.

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