Back to Curriculum
Also known asCRF-RB, CRF2, CRFR2, HM-CRF
CRHR2 (corticotropin-releasing hormone receptor 2) is a gene that codes for a protein called the corticotropin-releasing hormone receptor 2. This protein is found in various parts of the body, including the brain and the pituitary gland, and also plays a role in the body's response to stress. Like CRHR1, CRHR2 helps to regulate the release of hormones such as cortisol and adrenaline that are involved in the stress response. Variations in the CRHR2 gene have also been associated with an increased risk for certain mental health conditions, such as anxiety and depression. Studies suggest that CRHR2 may be involved in the regulation of emotional behavior and stress-related disorders, and could be a potential target for the development of new treatments for these conditions.