Gene AQP1
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Also known as
AQP-CHIP, CHIP28, COOverview
AQP1 is a gene that codes for the aquaporin 1 protein, a type of water channel found in cells throughout the body. This protein is part of a family of water channels known as aquaporins, which play a key role in the regulation of water transport across cell membranes. AQP1 is found in high levels in the epithelial cells of the kidney, the inner lining of blood vessels, and the lung, where it facilitates the movement of water across cell membranes and helps to regulate fluid balance. AQP1 is also involved in the regulation of blood pressure, blood volume, and other physiological processes. Mutations in the AQP1 gene have been linked to a number of disorders, including nephrogenic diabetes insipidus, a rare genetic condition that affects the ability of the kidney to concentrate urine and regulate fluid balance.