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Also known asADRB1R, B1AR, BETA1AR, FNSS2, RHR
ADRB1 is a gene that codes for the beta-1 adrenergic receptor, a protein located on the surface of cells in the heart, blood vessels, and lungs. This receptor plays a role in the regulation of cardiovascular and respiratory function by responding to signals from the hormone adrenaline and the neurotransmitter norepinephrine. Activation of the beta-1 adrenergic receptor triggers a cascade of events that result in increased heart rate, contractility, and relaxation of blood vessels, among other effects. Genetic variations in the ADRB1 gene have been associated with heart disease, hypertension, and other cardiovascular disorders.