Gene 5HT3B

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Also known as

HTR3B

Overview

5-HT3B is a gene that codes for a subunit of the 5-hydroxytryptamine 3 (5-HT3) receptor, which is a type of ligand-gated ion channel that is activated by the neurotransmitter serotonin. The 5-HT3 receptor is a pentameric receptor that is composed of five subunits, and the 5-HT3B subunit is thought to play a role in the assembly and function of the 5-HT3 receptor. The 5-HT3 receptor is widely expressed in the central and peripheral nervous systems and is involved in a number of important physiological functions, including the regulation of nausea and vomiting, pain perception, and memory and learning. Dysregulation of the 5-HT3 receptor has been linked to a number of disorders, including anxiety, depression, and substance abuse.

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