Silica - NutraPedia

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Silica: An Overview

1) Conditions Studied for Silica Use

Silica, also known as silicon dioxide, has been studied for a variety of health-related conditions. These include bone disorders such as osteoporosis, cardiovascular health, hair and nail strength, and skin conditions. It is also researched for its role in the prevention of cognitive decline, aluminum detoxification, and digestive health.

2) Efficacy of Silica in Treating Conditions

The efficacy of silica in treating the aforementioned conditions is mixed and often depends on the form of silica and the method of administration. For bone health, some studies suggest that silica may help in the formation of collagen and bone mineralization. However, more research is needed to establish its effectiveness conclusively for cardiovascular health, hair, nail strength, and other conditions.

3) Health Benefits of Silica

Silica is known for its potential health benefits, which include:

  • Promoting bone health and potentially reducing the risk of osteoporosis.
  • Supporting skin elasticity and collagen production.
  • Improving hair and nail quality by contributing to their strength and resilience.
  • Possibly aiding in the detoxification of aluminum in the body.
  • Supporting cognitive function and preventing neurodegenerative diseases.

4) Downsides of Silica

While silica is generally recognized as safe, there are some potential downsides, such as:

  • Excessive intake of silica may lead to silicosis, a lung disease, especially in occupational settings where inhalation of crystalline silica dust occurs.
  • High levels of silica in drinking water may be associated with an increased risk of dementia.
  • Some forms of silica used in supplements may not be well absorbed by the body.
  • Supplemental silica may interact with certain medications, so it is essential to consult with healthcare providers before starting supplementation.

5) Silica in Relation to Genetic Variations

Research on the interaction between silica and specific genetic variations is still in its early stages. Some studies suggest that genetic factors can influence the metabolism and effects of silica in the body, but conclusive evidence on whether silica is particularly beneficial or harmful for certain genetic variations is currently lacking. As personalized medicine evolves, understanding these genetic interactions with silica may become clearer.

Research Summary on Silica

Antioxidant Effects of Silica Hydride Supplements

A study assessing the antioxidant capabilities of Mega-H silica hydride, a dietary supplement, showed that it significantly reduces free radical activity in cell cultures. The supplement decreased singlet oxygen activity by over 96% and hydroxyl/superoxide radical activity by over 86%. This was determined using a technique that measured cell survival and toxicity. Untreated control cells had less than 1% viability, whereas cells treated with silica hydride had high viability, demonstrating the supplement's potent antioxidant properties.

Correlation Between Silica in Water and Cognitive Health

An analysis of 3,777 elderly French subjects indicated that high levels of aluminum in drinking water could be harmful to cognitive function, especially when silica levels are low. However, when both silica and the water's pH are high, aluminum may have a protective effect. The study highlighted a low threshold (3.5 micrograms per liter) for aluminum's impact, challenging the belief that only high levels are detrimental. No significant correlations were found between cognitive impairment and other minerals, except for an inverse relationship with calcium levels.

Effects of a Silicate Mineral Supplement on Exercise Responses

A clinical trial explored the cardiovascular responses to exercise after taking a dietary supplement called Microhydrin. This silicate mineral supplement, believed to have antioxidant properties, was tested on bicycle-trained participants through a double-blind, placebo-controlled trial. Although there were no significant differences in exercise performance, heart rate, oxygen uptake, or perceived exertion, the subjects had significantly lower blood lactate levels post-exercise after consuming Microhydrin. This suggests that the supplement could positively influence lactate metabolism during physical activity.

References:


  1. Antioxidant capability and efficacy of Mega-H silica hydride, an antioxidant dietary supplement, by in vitro cellular analysis using photosensitization and fluorescence detection
  2. Silica and aluminum in drinking water and cognitive impairment in the elderly
  3. Clinical Effects of a Dietary Antioxidant Silicate Supplement, Microhydrin((R)), on Cardiovascular Responses to Exercise


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