Red Light Therapy - NutraPedia

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Red Light Therapy: An Overview

1) Conditions Studied for Red Light Therapy

Red light therapy has been studied for a variety of conditions, including:

  • Skin conditions, such as acne, wrinkles, and scars
  • Pain relief, particularly for chronic inflammatory conditions like arthritis
  • Muscle recovery and injuries
  • Joint disorders
  • Depression and mood disorders linked with seasonal affective disorder (SAD)
  • Cognitive function improvement
  • Hair growth promotion

2) Effectiveness of Red Light Therapy

Studies on red light therapy show varying results:

  • There is evidence suggesting its effectiveness in wound healing, reducing inflammation, and improving skin complexion.
  • Some studies support its use in pain management and muscle recovery.
  • However, more research is needed to conclusively determine its effectiveness for various conditions.

3) Health Benefits of Red Light Therapy

The potential health benefits of red light therapy include:

  • Enhanced skin health and appearance
  • Reduced pain and inflammation
  • Improved muscle recovery
  • Increased collagen production
  • Stimulation of hair growth
  • Potential mood and cognitive function enhancement

4) Downsides of Red Light Therapy

While red light therapy is generally considered safe, there are some downsides:

  • Limited conclusive evidence on long-term effects and effectiveness for some conditions
  • Potential for overuse, which could lead to skin damage
  • Cost of treatment sessions or at-home devices can be high
  • Not covered by insurance as a treatment modality

5) Red Light Therapy and Genetic Variations

As of the current knowledge cutoff, there are no well-established links between red light therapy and specific genetic variations. However, individual responses to red light therapy may vary, which could potentially be influenced by genetics:

  • Some genetic factors may affect skin sensitivity or healing rates, potentially modifying the effectiveness of red light therapy.
  • More research is needed to understand the interaction between genetics and the benefits or risks of red light therapy.

Summary of Research on Red Light Therapy

Effectiveness in Treating Osteoarthritis: Red Light Therapy (RLT), also known as Low-Level Laser Therapy (LLLT), has been shown to significantly reduce pain and disability in patients with knee osteoarthritis (KOA) when specific doses and wavelengths are used. The most substantial pain relief occurs 2-4 weeks after therapy completion, with no adverse events reported.

Effectiveness in Treating Back Pain: LLLT is effective for pain relief in patients with nonspecific chronic low back pain but does not show improvements in function or mobility.

Effectiveness in Treating Neck Pain: RLT provides immediate pain relief after treatment in cases of acute neck pain and continues to provide relief for up to 22 weeks in chronic neck pain cases.

Effectiveness in Treating Fibromyalgia: RLT is an effective treatment for fibromyalgia, significantly improving pain severity, the number of tender points, fatigue, stiffness, depression, and anxiety compared to placebo. Combining RLT with a standardized exercise program does not provide additional benefits over exercise alone.

Effectiveness in Treating Tendinopathy: LLLT is potentially effective for tendinopathy treatment when used at recommended dosages.

Effectiveness in Treating Rheumatoid Arthritis: LLLT may be considered for short-term pain and morning stiffness relief in rheumatoid arthritis (RA) patients with minimal side effects.

Effectiveness in Treating Headaches: There is not enough evidence to support the use of photobiomodulation in treating primary headaches, and more rigorous randomized trials are needed.

Effectiveness in Post-Surgery Recovery: Photobiomodulation therapy (PBMt) effectively decreases pain intensity and inflammation following total hip arthroplasty.

Effectiveness in Treating Hair Loss: RLT seems to be an effective treatment for pattern hair loss in both men and women with generally safe devices.

Effectiveness in Managing Childhood Myopia: Repeated low-level red light (RLRL) therapy significantly reduces axial length and increases spherical equivalent refraction, effectively slowing the progression of myopia in children.

Effectiveness in Preventing Myopia: RLRL therapy reduces the incidence of myopia by a significant percentage in premyopic children and is an effective preventative method.

Long-term Efficacy in Slowing Myopia Progression: RLRL therapy appears to be effective in delaying myopia progression in children, but evidence is of low certainty. Further studies are recommended.

Effectiveness in Treating Age-Related Macular Degeneration (AMD): RLT significantly improves visual acuity in AMD patients without causing adverse side effects.

Use in Dermatology and Tissue Repair: RLT is beneficial in dermatology for conditions like wrinkles, acne scars, and inflammatory diseases. Its use in tendon injury treatment promotes repair but requires further understanding to optimize its use.

Penetration and Irradiation Studies: Studies show that light penetration in tissue increases with wavelength and is influenced by various factors such as beam width and skin tone. Effective medical use of light requires an understanding of these properties.

References:


  1. Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials
  2. The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis
  3. Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials
  4. Low-Level Laser Therapy for Fibromyalgia: A Systematic Review and Meta-Analysis
  5. Low level laser treatment of tendinopathy: a systematic review with meta-analysis
  6. Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis
  7. Photobiomodulation for the Treatment of Primary Headache: Systematic Review of Randomized Clinical Trials
  8. Photobiomodulation therapy (PBMT) on acute pain and inflammation in patients who underwent total hip arthroplasty-a randomized, triple-blind, placebo-controlled clinical trial
  9. Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature
  10. A Systematic Review and Meta-analysis of Randomized Controlled Trials of United States Food and Drug Administration-Approved, Home-use, Low-Level Light/Laser Therapy Devices for Pattern Hair Loss: Device Design and Technology
  11. Repeated Low-Level Red Light Therapy for the Control of Myopia in Children: A Meta-Analysis of Randomized Controlled Trials
  12. Effect of Repeated Low-level Red Light on Myopia Prevention Among Children in China With Premyopia: A Randomized Clinical Trial
  13. Efficacy of Repeated Low-Level Red-Light Therapy for Slowing the Progression of Childhood Myopia: A Systematic Review and Meta-analysis
  14. Low-level laser therapy improves vision in patients with age-related macular degeneration
  15. Therapeutic benefits of infrared (810-nm) diode laser macular grid photocoagulation in prophylactic treatment of nonexudative age-related macular degeneration: two-year results of a randomized pilot study
  16. A DOUBLE-MASKED, RANDOMIZED, SHAM-CONTROLLED, SINGLE-CENTER STUDY WITH PHOTOBIOMODULATION FOR THE TREATMENT OF DRY AGE-RELATED MACULAR DEGENERATION
  17. Effectiveness of non-pharmacological therapies on cognitive function in patients with dementia-A network meta-analysis of randomized controlled trials
  18. Transcranial Photobiomodulation Improves Cognitive Performance in Young Healthy Adults: A Systematic Review and Meta-Analysis
  19. Retinal Damage After Repeated Low-level Red-Light Laser Exposure
  20. Safety of light emitting diode-red light on human skin: Two randomized controlled trials
  21. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring
  22. The Functions and Mechanisms of Low-Level Laser Therapy in Tendon Repair (Review)
  23. Biological effects of low level laser therapy
  24. Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods
  25. Effect of Different Wavelengths of Laser Irradiation on the Skin Cells
  26. Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain?
  27. Skin penetration time-profiles for continuous 810 nm and Superpulsed 904 nm lasers in a rat model
  28. Infrared and skin: Friend or foe
  29. Defining skin aging and its risk factors: a systematic review and meta-analysis
  30. UV light and skin aging
  31. Visible light. Part II: Photoprotection against visible and ultraviolet light
  32. An appraisal of the need for infrared radiation protection in sunscreens
  33. Sunscreens and Photoaging: A Review of Current Literature
  34. Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis
  35. Effect of low-level laser therapy on muscle adaptation to knee extensor eccentric training
  36. Effects of photobiomodulation therapy associated with resistance training in elderly men: a randomized double-blinded placebo-controlled trial
  37. Low level laser therapy associated with a strength training program on muscle performance in elderly women: a randomized double blind control study
  38. Improvement of Performance and Reduction of Fatigue With Low-Level Laser Therapy in Competitive Cyclists
  39. Photobiomodulation Therapy Improves Performance and Accelerates Recovery of High-Level Rugby Players in Field Test: A Randomized, Crossover, Double-Blind, Placebo-Controlled Clinical Study
  40. Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress
  41. Infrared Low-Level Laser Therapy (Photobiomodulation Therapy) before Intense Progressive Running Test of High-Level Soccer Players: Effects on Functional, Muscle Damage, Inflammatory, and Oxidative Stress Markers-A Randomized Controlled Trial
  42. Whole-body photobiomodulation improves post-exercise recovery but does not affect performance or physiological response during maximal anaerobic cycling
  43. Photobiomodulation 30 min or 6 h Prior to Cycling Does Not Alter Resting Blood Flow Velocity, Exercise-Induced Physiological Responses or Time to Exhaustion in Healthy Men
  44. Acute Photobiomodulation Does Not Influence Specific High-Intensity and Intermittent Performance in Female Futsal Players
  45. Photobiomodulation Therapy at 808 nm Does Not Improve Biceps Brachii Performance to Exhaustion and Delayed-Onset Muscle Soreness in Young Adult Women: A Randomized, Controlled, Crossover Trial
  46. Pre-Exercise Infrared Low-Level Laser Therapy (810 nm) in Skeletal Muscle Performance and Postexercise Recovery in Humans, What Is the Optimal Dose? A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
  47. Effects of Laser Acupuncture on Delayed Onset Muscle Soreness of the Biceps Brachii Muscle: A Randomized Controlled Trial
  48. Light-based therapies in acne treatment
  49. Comparison of red light and blue light therapies for mild-to-moderate acne vulgaris: A randomized controlled clinical study
  50. Efficacy of photodynamic therapy for the treatment of inflammatory acne vulgaris: A systematic review and meta-analysis
  51. Comparison of Red and Infrared Low-level Laser Therapy in the Treatment of Acne Vulgaris
  52. The Anti-Acne Effect of Near-Infrared Low-Level Laser Therapy
  53. Red light phototherapy alone is effective for acne vulgaris: randomized, single-blinded clinical trial
  54. Photobiomodulation invigorating collagen deposition, proliferating cell nuclear antigen and Ki67 expression during dermal wound repair in mice
  55. Long-term evaluation of collagen and elastin following infrared (1100 to 1800 nm) irradiation
  56. Light-emitting diodes in dermatology: A systematic review of randomized controlled trials
  57. LED photoprevention: reduced MED response following multiple LED exposures


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