Kokilaksha - NutraPedia

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Kokilaksha (Hygrophila auriculata) Overview

1) Studied Conditions

Kokilaksha, also known as Hygrophila auriculata, has been traditionally used in Ayurveda and has been studied for several conditions. These include:

  • Sexual dysfunction and fertility issues
  • Urinary tract disorders
  • Liver disorders
  • Rheumatic pain
  • General inflammation

2) Effectiveness in Treating Conditions

While traditional use suggests some benefits, scientific evidence is limited. Some studies have shown promise in treating conditions like sexual dysfunction and anti-inflammatory effects, but more research is needed to conclusively determine its effectiveness.

3) Health Benefits

Health benefits attributed to Kokilaksha include:

  • Enhancing libido and sexual performance
  • Diuretic properties that may help in urinary disorders
  • Potential hepatoprotective effects on the liver
  • Anti-inflammatory and analgesic properties
  • May improve sperm count and motility

4) Downsides

Although Kokilaksha is generally considered safe when used in traditional medicine, it can have downsides, including:

  • Possible interactions with other medications
  • Insufficient information on its safety profile for pregnant or breastfeeding women
  • Rare reports of side effects such as gastrointestinal upset
  • Lack of standardization in dosages and formulations

5) Genetic Variations and Impact

There is limited research on the interaction between Kokilaksha and specific genetic variations. Some herbal compounds can have different effects based on an individual's genetic makeup, but as of now, there is no concrete evidence to suggest that Kokilaksha is particularly beneficial or harmful for any specific genetic variations.

Research Summary on Kokilaksha (Asteracantha longifolia)

Kokilaksha, also known as Asteracantha longifolia, is a medicinal plant that has been the subject of various studies to explore its potential health benefits.

Effects on Male Sexual Behavior

One study investigated the effects of Asteracantha longifolia seed extract on male rat sexual behavior, finding that the extract improved sexual performance, increased sperm production, and enhanced sexual function.

Chemical Compounds in Medicinal Plants

Another study examined the presence of chemical compounds in Asteracantha longifolia and other Indian medicinal plants. It was found that while all plants contained several important compounds, Asteracantha longifolia did not have flavonoids and terpenoids.

Liver Cancer Prevention

One research focused on the prevention of liver cancer in rats, showing that a methanol extract from Asteracantha longifolia seeds significantly reduced tumor growth and improved antioxidant enzyme function.

Treatment of Rheumatoid Arthritis

The effectiveness of Asteracantha longifolia in treating Rheumatoid Arthritis symptoms was highlighted, with a traditional preparation from this plant shown to alleviate symptoms, particularly in the initial stages of the disease.

Neuroprotective and Antioxidant Effects

A study on the neuroprotective and antioxidant effects of a terpenoid fraction extracted from Hygrophila auriculata (another name for Asteracantha longifolia) indicated that it could counteract oxidative stress induced by cerebral ischemia.

Iron Deficiency Anemia

Research supported the traditional use of Asteracantha longifolia in managing iron deficiency anemia, with the plant's extract improving red blood cell count and hemoglobin levels in anemia-induced rats.

Antidiabetic and Antioxidant Properties

A study on the antidiabetic and antioxidant properties of Hygrophila auriculata showed that it significantly reduced blood glucose levels and oxidative stress markers in diabetic rats.

Hepatoprotective Properties

Multiple studies have demonstrated the hepatoprotective properties of Asteracantha longifolia extracts, showing their effectiveness in preventing and reducing liver damage caused by various hepatotoxic agents in animal models.

In summary, the research on Kokilaksha (Asteracantha longifolia) suggests that it possesses a variety of medicinal properties, including enhancing sexual function, preventing liver cancer, treating Rheumatoid Arthritis, providing neuroprotection, managing iron deficiency anemia, offering antidiabetic and antioxidant benefits, and protecting the liver from damage.


  1. Effect of Asteracantha longifolia seeds on the sexual behaviour of male rats
  2. Preliminary phytochemical screening of some Indian Medicinal Plants
  3. On Hygrophila Spinosa (Vel Asteracantha Longifolia)
  4. Anti-tumor promoting activity of Asteracantha longifolia against experimental hepatocarcinogenesis in rats
  5. Constituents of Asteracantha longifolia
  6. Rheumatoid arthritis and astercantha longifolia
  7. Neuroprotective and antioxidant potential of terpenoid fraction from Hygrophila auriculata against transient global cerebral ischemia in rats
  8. Erythropoietic activity of Asteracantha longifolia (Nees.) in rats
  9. Action of Hygrophila auriculata against streptozotocin-induced oxidative stress
  10. Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients
  11. Hepatoprotective and antioxidant effects of Hygrophila auriculata (K. Schum) Heine Acanthaceae root extract
  12. In vitro and in vivo hepatoprotective effects of the total alkaloid fraction of Hygrophila auriculata leaves
  13. Hepatoprotective activity of Apium graveolens and Hygrophila auriculata against paracetamol and thioacetamide intoxication in rats
  14. Evaluation of the protective efficacy of Asteracantha longifolia on acetaminophen-induced liver damage in rats
  15. Protective effect of Asteracantha longifolia extract in mouse liver injury induced by carbon tetrachloride and paracetamol
  16. Effect of Asteracantha longifolia Nees. against CCl4 induced liver dysfunction in rat

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