N-acetylcysteine (NAC) - NutraHacker Journal Club

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Genotypic and phenotypic spectrum of infantile liver failure due to pathogenic TRMU variants - PubMed (nih.gov)



GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage - PubMed (nih.gov)



Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial - PubMed (nih.gov)



A Randomized Controlled Clinical Trial in Healthy Older Adults to Determine Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage - PubMed (nih.gov)



Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine - PubMed (nih.gov)



N‐acetylcysteine replenishes glutathione in HIV infection - De Rosa - 2000 - European Journal of Clinical Investigation - Wiley Online Library



GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging - PubMed (nih.gov)



Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial - PubMed (nih.gov)



GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study - PubMed (nih.gov)



Successful use of N-acetylcysteine to treat severe hepatic injury caused by a dietary fitness supplement - PubMed (nih.gov)



Late extensive intravenous administration of N-acetylcysteine can reverse hepatic failure in acetaminophen overdose - PubMed (nih.gov)



Paracetamol overdose: the liver unit perspective - PubMed (nih.gov)



Successful treatment of acetaminophen overdose associated with hepatic failure - PubMed (nih.gov)



Paracetamol self-poisoning: when oral N-acetylcysteine saves life? a case report - PubMed (nih.gov)



Use of N-Acetylcysteine in Amphetamine-Induced Acute Liver Failure - PubMed (nih.gov)



N-Acetylcysteine (NAC): Impacts on Human Health - PubMed (nih.gov)



N-acetylcysteine in non-acetaminophen-induced acute liver failure: a systematic review and meta-analysis of prospective studies - PubMed (nih.gov)



The Roles of Antidotes in Emergency Situations - PubMed (nih.gov)



Use of N-Acetylcysteine in Amphetamine-Induced Acute Liver Failure - PubMed (nih.gov)



Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceuticals: A Practical Strategy for Preserving Bone Mass - PubMed (nih.gov)



Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients - PubMed (nih.gov)



N-acetylcysteine as a treatment for amatoxin poisoning: a systematic review - PubMed (nih.gov)



Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits - PubMed (nih.gov)



A minireview on N-acetylcysteine: An old drug with new approaches - PubMed (nih.gov)



Evaluation of the antioxidant properties of N-acetylcysteine in human platelets: prerequisite for bioconversion to glutathione for antioxidant and antiplatelet activity - PubMed (nih.gov)



N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why - PubMed (nih.gov)



Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease - PubMed (nih.gov)



Pharmacokinetics of N-acetylcysteine in man | SpringerLink



Safety of N-Acetylcysteine at High Doses in Chronic Respiratory Diseases: A Review - PMC (nih.gov)



Iron, Neuroinflammation and Neurodegeneration - PubMed (nih.gov)



Mitochondrial modulators for obsessive-compulsive and related disorders: a systematic review and meta-analysis - PubMed (nih.gov)



N-Acetylcysteine in the Treatment of Excoriation Disorder: A Randomized Clinical Trial - PubMed (nih.gov)



N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study - PubMed (nih.gov)



Dramatic Improvement of Trichotillomania with 6 Months of Treatment With N-Acetylcysteine - PubMed (nih.gov)



The Potential of N-Acetyl-L-Cysteine (NAC) in the Treatment of Psychiatric Disorders - PubMed (nih.gov)



N-acetylcysteine as a new prominent approach for treating psychiatric disorders - PubMed (nih.gov)



Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review - PubMed (nih.gov)



Subchronic N-acetylcysteine Treatment Decreases Brain Kynurenic Acid Levels and Improves Cognitive Performance in Mice - PubMed (nih.gov)



N-Acetylcysteine Inhibits Kynurenine Aminotransferase II - PubMed (nih.gov)



Kynurenic acid and kynurenine aminotransferases in retinal aging and neurodegeneration - PubMed (nih.gov)



L-NAC reverses of the adverse effects of fentanyl infusion on ventilation and blood-gas chemistry - PubMed (nih.gov)



Role of kynurenines in the central and peripheral nervous systems - PubMed (nih.gov)



Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases - PubMed (nih.gov)



Oxidative Stress in Chronic Obstructive Pulmonary Disease - PubMed (nih.gov)



N-acetyl cysteine as a potential regulator of SARS-CoV-2-induced male reproductive disruptions - PubMed (nih.gov)



The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione - PubMed (nih.gov)



N-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis - PubMed (nih.gov)



N-Acetylcysteine Mitigates Social Dysfunction in a Rat Model of Autism Normalizing Glutathione Imbalance and the Altered Expression of Genes Related to Synaptic Function in Specific Brain Areas - PubMed (nih.gov)



Medical and Dietary Uses of N-Acetylcysteine - PubMed (nih.gov)



Effects of N-acetylcysteine on sucrose-rich diet-induced hyperglycaemia, dyslipidemia and oxidative stress in rats - ScienceDirect



Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats - PubMed (nih.gov)



Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: effect of membrane physical properties and S-adenosyl-L-methionine - PubMed (nih.gov)



Supplementation with a Specific Combination of Metabolic Cofactors Ameliorates Non-Alcoholic Fatty Liver Disease, Hepatic Fibrosis, and Insulin Resistance in Mice - PubMed (nih.gov)



The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol and N-acetylcysteine Are the Preventers - PubMed (nih.gov)



N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks) - PubMed (nih.gov)

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